Infection at the aortic valve was independently associated with mortality by IE. Clinical cure was noted in 80.3%, while the overall mortality was 19.4%. Surgical treatment along with antimicrobials was performed in 37.3% of included patients. Cephalosporins, aminoglycosides, and carbapenems were the most frequently used antimicrobials. Fever and sepsis were the most frequent clinical presentations, followed by embolic phenomena, paravalvular abscess, and heart failure. The diagnosis was based on transthoracic echocardiography in 46.2%, while the diagnosis was set at autopsy in 9.2% of included patients. The aortic valve was the most commonly infected intracardiac site, followed by the mitral valve. A prosthetic valve was present in 16.4%, while the most common causative pathogen was K. In this review, a total of 66 studies were included, providing data for 67 patients. A systematic review of PubMed, Scopus and Cochrane library (through 27th January 2021) for studies providing epidemiological, clinical, microbiological as well as treatment data and outcomes of IE by Klebsiella species was performed. Available from: (accessed Jan 2020).This study aimed to systematically analyze all cases of infective endocarditis (IE) by Klebsiella species in the literature. Department of Health and Human Services, CDC, 2019. Centers for Disease Control and Prevention (CDC). Efficacy of Antitoxin Therapy in Treating Patients With Foodborne Botulism: A Systematic Review and Meta-analysis of Cases, 1923-2016. O'Horo JC, Harper EP, El Rafei A, Ali R, DeSimone DC, Sakusic A, et al. Respiratory failure caused by wound botulism likely occurring from a contaminated freshwater wound. Wound botulism associated with black tar heroin among injecting drug users.
TOMOGRAFIA COMPUTARIZADA SIN CONTRASTE MAC
Passaro DJ, Werner SB, McGee J, Mac Kenzie WR, Vugia DJ. Wound botulism among black tar heroin users-Washington, 2003. Images in clinical medicine: Wound botulism. Wound botulism associated with subcutaneous drug use. Merrison AF, Chidley KE, Dunnett J, Sieradzan KA. Treasure Island (FL): StatPearls Publishing 2021.Ħ. Wound botulism: still a challenge to diagnose. Clostridium botulinum: an increasing complication of heroin misuse. Cooper JG, Spilke CE, Denton M, Jamieson S. Se descubrió una colonia de especies de Clostridium en el brazo de esta paciente, mostrando una mejoría significativa después de unos días de atención. Se le administró antitoxina de botulismo y la paciente fue ingresada en la unidad de cuidados intensivos para cuidados de seguimiento de apoyo. Sin hallazgos destacables de la tomografía computarizada sin contraste y la resonancia magnética y ante la sintomatología, se realizó el diagnóstico de botulismo de la herida por uso de drogas intravenosas.
El paciente refiere antecedentes de abuso de múltiples sustancias por vía intravenosa y los síntomas progresaron a debilidad facial bilateral, ptosis y oftalmoplejía externa. Una mujer de 41 años presentó quejas de aparición repentina de dificultad para hablar. El propósito de este informe de caso clínico es garantizar que el botulismo del adulto se incluya en los diagnósticos diferenciales de un paciente con esta presentación, de modo que se pueda brindar una atención rápida y precisa para garantizar un resultado óptimo del paciente. La presentación del botulismo en adultos es extremadamente rara y los síntomas pueden confundirse fácilmente con los síntomas de accidente cerebrovascular agudo, Guillain-Barré o miastenia gravis. A colony of Clostridium species was discovered in this patient’s arm and the patient showed significant improvement after a few days of care. Botulism antitoxin was given and the patient was admitted into the intensive care unit for supportive follow-up care. With no notable findings from a non-contrast computed tomography and magnetic resonance imaging and given the symptoms, a diagnosis of wound botulism from intravenous drug use was made. The patient reports a history of intravenous polysubstance abuse and symptoms progressed to bilateral facial weakness, ptosis, and external ophthalmoplegia. A 41-year-old-female presented with complaints of sudden onset of difficulty speaking. The purpose of this clinical case report is to ensure adult botulism will be included in the differential diagnoses for a patient with this presentation so swift and accurate care can be provided to ensure optimal patient outcome. Presentation of botulism in adults is extremely rare and symptoms can be easily confused for symptoms of acute stroke, Guillain-Barre, or myasthenia gravis.
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